• Research Professor, Global Health
  • Professor and Program Head, Fred Hutchinson Cancer Research Center
Paul Lampe

Fred Hutchinson Cancer Research Center
1100 Fairview Ave N
Box 358080
Seattle, WA 98109
United States

Phone Number: 
206-667-4123
Fax: 
Email: 
lampep@uw.edu
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Biography 

Paul Lampe is Full Member and Head of the Translational Research Program in the Public Health Sciences Division at Fred Hutchinson Cancer Research Center and Research Professor at the University of Washington. His laboratory investigates the control of cell growth both at the cell biological/mechanistic level and through cancer biomarker discovery. The advent of new high data content methodologies has expanded his efforts into broad screens using high density antibody array technologies to discover proteomic, autoantibody and glycomic biomarkers and properties of cancer. The laboratory is funded by multiple grants from NIH some of which involve collaborations with epidemiologists (Christopher Li, Neli Ulrich), nutritionists (Johanna Lampe, Marian Neuhouser) and clinicians (McGarry Houghton, Sunil Hingorani, William Grady, Charles Drescher). Most of the “omic” work focuses on discovery and validation of early detection biomarkers of colon, lung, breast and pancreas cancer.

See the Paul Lampe Lab website for more information.

Education 
  • PhD (University of Minnesota)
  • BA (Carleton College)
Country Affiliations 
Languages 
  • German
Health Topics 
  • Cancer
  • Pathobiology
Pathobiology research areas 
DGH Centers, Programs and Initiatives and Affiliated Organizations 
Publications 

a. Solan JL, Márquez-Rosado L, Lampe PD (2019) “Cx43 phosphorylation mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter stability of stress-inducible protein NDRG1”. J. Biol. Chem. 294(31) 11762–11771. PMC6682735

b. Rho JH, Ladd JJ, Li CI, Potter JD, Zhang Y, Shelley D, Shibata D, Coppola D, Yamada H, Toyoda H, Tada T, Kumada T, Brenner DE, Hanash SM, Lampe PD. (2018) Protein and glycomic plasma markers for early detection of adenoma and colon cancer. Gut, 67: 473-484. PMC5420499.

c. Lastwika KJ, Kargl J, Zhang Y, Zhu X, Lo E, Shelley D, Ladd JJ, Wu W, Kinahan P, Pipavath SNJ, Randolph TW, Shipley M, Lampe PD, Houghton AM. Tumor-Derived Autoantibodies Identify Malignant Pulmonary Nodules. Am J Respir Crit Care Med. 2019 May 15;199(10):1257-1266. PMC6519849.

d. Mirus JE, Zhang Y, Li CI, Lokshin AE, Prentice RL, Hingorani SR, Lampe PD. Cross-species antibody microarray interrogation identifies a 3-protein panel of plasma biomarkers for early diagnosis of pancreas cancer. Clin Cancer Res. 2015 Apr 1;21(7):1764-71. PMC4391639.