• Associate Professor, Global Health
  • Adjunct Associate Professor, Epidemiology

Seattle, WA
United States

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Paul Drain, MD, MPH, is Associate Professor in the Departments of Global Health, Medicine (Infectious Diseases), and Epidemiology at the University of Washington and a practicing Infectious Disease physician at Harborview Medical Center and the University of Washington Medical Center in Seattle. His research group focuses on development, evaluation and implementation of diagnostic testing and clinic-based screening, including novel point-of-care technologies, to improve clinical care and patient-centered outcomes for tuberculosis and HIV in resource-limited settings.

He is Associate Director of the Tuberculosis Research and Training Center at the University of Washington and teaches the “Clinical Global Health and Social Medicine” course for medical students. He research has been supported by several institutes of the National Institutes of Health, the Infectious Disease Society of America, Bill and Melinda Gates Foundation, Harvard Global Health Institute, both the UW’s and Harvard’s Center for AIDS Research, and the AIDS Healthcare Foundation.

He has authored several global health books and received a Faculty Teaching Award from Harvard Medical School.

  • MD (University of Washington)
  • MPH (University of Washington)
  • BA (Miami University (Ohio))
Health Topics 
  • Bioengineering
  • Clinical Mentoring
  • Community-Based Primary Health Care
  • COVID-19
  • Epidemiology
  • Global Health Governance
  • Health Interventions
  • Health Systems Strengthening and Human Resources Development
  • Health Technologies
  • Host-Pathogen Interactions
  • HPV
  • Immunizations
  • Infectious Diseases
  • Infectious Diseases (other than STDs)
  • Modeling
  • Operations Research
  • Pulmonary Diseases and Pneumonia
  • Respiratory Disease
  • Social Determinants of Health
  • STDs (other than HIV)
  • TB
  • Viruses

Drain PK, Hyle EP, Noubary F, Freedberg KA, Wilson D, Bishai WR, Rodriguez W, Bassett IV. Diagnostic point-of-care tests in resource-limited settings. Lancet Infect Dis. 2014;14:239-49 [original work]. doi: 10.1016/S1473-3099(13)70250-0. PMCID: 4016042.

Drain PK, Kubiak RW, Siriprakaisil O, Klinbuayaem V, Quame-Amaglo J, Sukrakanchana PO, Tanasri S, Punyati P, Siriungsi W, Cressey R, Bacchetti P, Okochi H, Baeten JM, Gandhi M, Cressey TR. Urine tenofovir concentrations correlate with plasma and relates to TDF adherence: A Randomized directly-observed pharmacokinetic trial (TARGET Study). Clin Infect Dis. Published online 17 Jul 2019. doi: 10.1093/cid/ciz645.

Gandhi M, Bacchetti P, Spinelli M, Okochi H, Baeten JM, Sirirakaisal O, Klinbuayaem V, Rodrigues WC, Wang G, Vincent M, Cressey TR, Drain PK. Validation of a urine tenofovir immunoassay for adherence monitoring to PrEP and ART and establishing the cutoff for a point-of-care test. J Acquir Immune Defic Syndr. 2019; 81:72-7. PMCID: 6456396.

Drain PK, Dorward J, Violette LR, Quame-Amaglo J, Thomas KK, Samsunder N, Ngobese H, Mlisana K, Moodley P, Donnell D, Barnabas RV, Naidoo K, Abdool Karim SS, Celum C, Garrett N; STREAM Study Team. Point-of-care HIV viral load testing combined with task shifting to improve treatment outcomes (STREAM): findings from an open-label, non-inferiority, randomised controlled trial. Lancet HIV. 2020;7:e229-37 [original work]. doi: 10.1016/S2352-3018(19)30402-3. PMCID: 7183312