- Adjunct Associate Professor, Global Health
- Associate Professor, Pediatrics - Emergency Medicine
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My major academic interests are in the development of a better understanding of the pathophysiology underlying chronic and acute childhood malnutrition, improving the diagnosis and treatment of malnourished children, and improvements in the diagnosis and management of tropical infectious diseases. The majority of my research experience in these domains has come in the conduct of large clinical trials in rural Malawi as well as in smaller hospital-based cohort studies to complement my clinical experience caring for children and adults in austere settings around the world. I serve as an advisor and consultant to UNICEF, Action Against Hunger, Médecins Sans Frontières, the Alliance for International Medical Action, and Friends Without a Border.
My clinical work abroad has spanned numerous countries and settings, including emergency care in Haiti, directing an Ebola Treatment Centre in Sierra Leone, and primary care in a Rohingya refugee camp in Bangladesh, but I am most passionate about training of local health care providers in evidence-based cost-effective care that maximizes survival and human potential. I took an academic sabbatical to manage clinical operations in rural Liberia for Partners in Health and then as the Medical Director and Executive Director of Lao Friends Hospital for Children in 2017-2019, before moving to Seattle in January 2020.
- BS (University of California (Berkeley))
- Child and Adolescent Health (incl. Pediatrics)
- Child Mortality
- Clinical Mentoring
- Community Health Workers
- Diarrheal Diseases
- Education and Training
- Emergency Medicine
- Health Policy and Advocacy
- Health Systems Strengthening and Human Resources Development
- Health Technologies
- Infectious Diseases
- Injury, Violence, Trauma and Domestic Violence
- Laboratory Strengthening
- Maternal Child Health (incl. Reproductive Health)
- Neglected Diseases, Tropical Medicine (incl. Parasites)
- Nutrition, Clean Water, and Food Security
- Trop. Med (incl. Parasites)
LaGrone LN, Trehan I, Meuli GJ, Wang RJ, Thakwalakwa C, Maleta K, Manary MJ. A novel fortified blended flour, corn-soy blend "plus-plus," is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children. Am J Clin Nutr. 2012 Jan; 95(1):212-9. PMID: 22170366.
Yatsunenko T, Rey FE, Manary MJ, Trehan I, Dominguez-Bello MG, Contreras M, Magris M, Hidalgo G, Baldassano RN, Anokhin AP, Heath AC, Warner B, Reeder J, Kuczynski J, Caporaso JG, Lozupone CA, Lauber C, Clemente JC, Knights D, Knight R, Gordon JI. Human gut microbiome viewed across age and geography. Nature. 2012 May 9; 486(7402):222-7. PMID: 22699611.
Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJ. Antibiotics as part of the management of severe acute malnutrition. N Engl J Med. 2013 Jan 31; 368(5):425-35. PMID: 23363496.
Trehan I, Banerjee S, Murray E, Ryan KN, Thakwalakwa C, Maleta KM, Manary MJ. Extending supplementary feeding for children younger than 5 years with moderate acute malnutrition leads to lower relapse rates. J Pediatr Gastroenterol Nutr. 2015 Apr; 60(4):544-9. PMID: 25419681.
Cheng WD, Wold KJ, Bollinger LB, Ordiz MI, Shulman RJ, Maleta KM, Manary MJ, Trehan I. Supplementation with lactoferrin and lysozyme ameliorates environmental enteric dysfunction: A double-blind, randomized, placebo-controlled trial. Am J Gastroenterol. 2019 Apr; 114(4):671-8. PMID: 30829679.