• Adjunct Associate Professor, Global Health
  • Associate Professor, Medicine - Allergy and Infectious Dis.
  • Adjunct Associate Professor, Epidemiology

R&T Bldg, 300 9th Ave
Box 359779
Seattle, WA 98104
United States

Phone Number: 
206-685-8702
Fax: 
Email: 
helenchu@uw.edu
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Biography 

Dr. Chu's research is focused on maternal immunization, in particular vaccines against influenza and respiratory syncytial virus (RSV). She studies the virologic and immunologic correlates of protection from respiratory viral infections in pregnant women, infants, and older adults, and performs clinical trials of vaccine candidates in both domestic and international sites, including Nepal and Bangladesh. She has developed immunologic assays to study transplacental transfer and decay kinetics of RSV antibody, and nosocomial and household transmission of respiratory viruses by genotypic analysis and molecular sequencing.

Education 
  • MPH (University of Washington)
  • MD (Duke University Medical Center, Durham, NC)
  • BA (Cornell University)
Country Affiliations 
Health Topics 
  • Influenza
  • Maternal Child Health (incl. Reproductive Health)
  • Viruses
Publications 

Chu HY, Steinhoff MC, Magaret A, Zaman K, Roy E, Langdon G, Formica MA, Walsh EE, Englund JA. Respiratory syncytial virus transplacental antibody transfer and kinetics in mother-infant pairs in Bangladesh. J Infect Dis. 2014 Nov 15;210(10):1582-9. doi: 10.1093/infdis/jiu316. Epub 2014 Jun 5. PubMed PMID: 24903663; PubMed Central PMCID: PMC4334795.

Lenahan JL, Englund JA, Katz J, Kuypers J, Wald A, Magaret A, Tielsch JM, Khatry SK, LeClerq SC, Shrestha L, Steinhoff MC, Chu HY. Human Metapneumovirus and Other Respiratory Viral Infections during Pregnancy and Birth, Nepal. Emerg Infect Dis. 2017 Aug;23(8). doi: 10.3201/eid2308.161358. PubMed PMID: 28726613; PubMed Central PMCID: PMC5547777.

Mazur NI, Horsley NM, Englund JA, Nederend M, Magaret A, Kumar A, Jacobino SR, de Haan CAM, Khatry SK, LeClerq SC, Steinhoff MC, Tielsch JM, Katz J, Graham BS, Bont LJ, Leusen JHW, Chu HY. Breast Milk Prefusion F Immunoglobulin G as a Correlate of Protection Against Respiratory Syncytial Virus Acute Respiratory Illness. J Infect Dis. 2019 Jan 1;219(1):59-67. doi: 10.1093/infdis/jiy477. PubMed PMID: 30107412; PubMed Central PMCID: PMC6284547.

Murray AF, Englund JA, Kuypers J, Tielsch JM, Katz J, Khatry SK, Leclerq SC, Chu HY. Infant pneumococcal carriage during influenza, RSV and hMPV respiratory illness within a maternal influenza immunization trial. J Infect Dis. 2019 May 6;. doi: 10.1093/infdis/jiz212. [Epub ahead of print] PubMed PMID: 31056697.

Boonyaratanakornkit J, Ekici S, Magaret A, Gustafson K, Scott E, Haglund M, Kuypers J, Pergamit R, Lynch J, Chu HY. Respiratory Syncytial Virus Infection in Homeless Populations, Washington, USA. Emerg Infect Dis. 2019 Jul;25(7):1408-1411. doi: 10.3201/eid2507.181261. PubMed PMID: 31211675; PubMed Central PMCID: PMC6590761.