- Affiliate Assistant Professor
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Biography
Dr. Daphne Avgousti studies how viruses hijack the DNA packaging of the cells they infect. She works with adenovirus, a common cold virus, to address fundamental questions about how special proteins work to neatly compress DNA to fit inside cells or viruses. Specifically, she works on how viruses use these DNA-packaging proteins, also known as chromatin proteins, to manipulate the host to their own ends.
Education
- PhD (Columbia Unveristy)
DGH Centers, Programs and Initiatives and Affiliated Organizations
Publications
- Epigenetics and the dynamics of chromatin during adenovirus infections.Lynch KL, Gooding LR, Garnett-Benson C, Ornelles DA, Avgousti DCFEBS letters. 2019 Nov; :
- Identifying Host Factors Associated with DNA Replicated During Virus Infection.Reyes ED, Kulej K, Pancholi NJ, Akhtar LN, Avgousti DC, Kim ET, Bricker DK, Spruce LA, Koniski SA, Seeholzer SH, Isaacs SN, Garcia BA, Weitzman MDMolecular & cellular proteomics : MCP. 2017 Dec; 16 12: 2079-2097
- Differential Salt Fractionation of Nuclei to Analyze Chromatin-associated Proteins from Cultured Mammalian Cells.Herrmann C, Avgousti DC, Weitzman MDBio-protocol. 2017 Mar; 7 6:
- Adenovirus Core Protein VII Downregulates the DNA Damage Response on the Host Genome.Avgousti DC, Della Fera AN, Otter CJ, Herrmann C, Pancholi NJ, Weitzman MDJournal of virology. 2017 Oct; 91 20:
- Time-resolved Global and Chromatin Proteomics during Herpes Simplex Virus Type 1 (HSV-1) Infection.Kulej K, Avgousti DC, Sidoli S, Herrmann C, Della Fera AN, Kim ET, Garcia BA, Weitzman MDMolecular & cellular proteomics : MCP. 2017 04; 16 4 suppl 1: S92-S107